Project description:This SuperSeries is composed of the following subset Series: GSE28909: Genome wide analysis of acral melanoma (Illumina) GSE28910: Genome wide analysis of acral melanoma (Affymetrix) Refer to individual Series
Project description:Genotyping of a matched normal, primary and metastatic acral melanoma DNA from blood and one matched Primary and one metastatic acral melanoma was genotyped on Affmetrix SNP6
Project description:Assessment of mutation on expression levels Transcriptomic profile of a matched primary and metastatic acral melanoma One Primary and one metastatic acral melanoma transcript expression were assayed (no matched normal)
Project description:Acral melanoma is considered as a special subtype of melanoma. We performed 11 single cell RNA sequencing (scRNA seq), 57 Bulk RNA sequencing, 8 whole exon sequencing(WES seq), and 6 TCR sequencing to analyze the tumor heterogeneity and immune environment characteristics of acral melanoma.
Project description:Acral melanoma is considered as a special subtype of melanoma. We performed 11 single cell RNA sequencing (scRNA seq), 57 Bulk RNA sequencing, 8 whole exon sequencing(WES seq), and 6 TCR sequencing to analyze the tumor heterogeneity and immune environment characteristics of acral melanoma.
Project description:Acral melanoma is a rare subtype of melanoma that arises on the non-hair-bearing skin of the palms, soles and nail beds. In this study, we used single cell RNA-seq (scRNA-seq) to map the transcriptional landscape of acral melanoma and identify novel immunotherapeutic targets.