Project description:Bermudagrass (Cynodon dactylon L.) is an important warm-season turfgrass species with well-developed stolons, which lay the foundation for fast propagation of bermudagrass plants through asexually clonal growth. However, the growth and development of bermudagrass stolons are still poorly understood at the molecular level. In this study, we comprehensively analyzed the succinylation modifications of proteins in fast growing stolons of bermudagrass cultivar Yangjiang. A total of 226 lysine succinylation sites on 128 proteins were successfully identified using liquid chromatography coupled to tandem mass spectrometry.
Project description:Bermudagrass (Cynodon dactylon L.) is an important warm-season turfgrass species with well-developed stolons, which lay the foundation for fast propagation of bermudagrass plants through asexually clonal growth. However, the growth and development of bermudagrass stolons are still poorly understood at the molecular level. In this study, we comprehensively analyzed the acetylation modifications of proteins in fast growing stolons of bermudagrass cultivar Yangjiang. A total of 4657 lysine acetylation sites on 1914 proteins were successfully identified using liquid chromatography coupled to tandem mass spectrometry.
2022-08-20 | PXD034841 | Pride
Project description:Genome sequencing of common bermudagrass
Project description:Bermudagrass is an important warm-season turfgrass species with both erect growing shoots and prostrate growing stolons, however, the mechanism how bermudagrass shoots and stolons form and maintain their unique geotropic growth modes are still unclear. In this study, we compared the proteome of the internode section of shoots and stolons at the same developmental stage in bermudagrass cultivar Yangjiang. The results indicated that 376 protein species were differentially accumulated in the two types of stems.
Project description:As a widely used turfgrass species, bermudagrass (Cynodon dactylon L.) can be easily propagated by colonial growth of stolons. Previous studies collectively revealed that exotic environmental factors and intrinsic hormones and genes are all involved in the differentiation, development, and diageotropically growth of stolons. However, the detailed molecular mechanism how environmental and hormone signals regulate the gene expression and biochemical activities in bermudagrass stolons remains unclear. In this study, LC-MS/MS analyses of the total protein extracts of bermudagrass stolons without preliminary phosphopeptide-enrichment successfully identified 862 nonredundant phosphorylation sites and 613 phosphoproteins.
Project description:This study intends to explore the clinicopathological characteristics and survival prognosis of locally recurrent colorectal cancer patients with different treatment modes by retrospectively analyzing the medical records of locally recurrent colorectal cancer patients who received hospitalization in our center. Transcriptome sequencing and public databases were used to screen for molecular markers related to locally recurrent colorectal cancer and to explore molecular markers’ regulatory role in the progression of locally recurrent colorectal cancer.
Project description:In order to more accurately discover the cause of drug resistance in tumor treatment, and to provide a new basis for precise treatment.
Therefore, based on the umbrella theory of precision medicine, we carried out this single-center, prospective, and observational study to include patients with liver metastases from colorectal cancer. By combining genome, transcriptome, and proteomic sequencing data, we established a basis for colorectal cancer liver Transfer the multi-omics data of the sample, describe the reason for the resistance of the first-line treatment, and search for new therapeutic targets.