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MRNA sequencing of circCpsf6 silencing models in N2A cells

ABSTRACT: mRNA sequencing of circCpsf6 silencing models in N2A cells

PROVIDER: PRJNA688649 | ENA |

REPOSITORIES: ENA

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circCpsf6 silencing models in N2A cells

Project description:circCpsf6 silencing models in N2A cells

| PRJNA688647 | ENA

miRNA sequencing of circCpsf6 silencing models in N2A cells

Project description:To search and identify the potential downstream miRNAs of circCpsf6, miRNA sequencing analysis was performed on circCpsf6 silencing models in N2A cells. The differential expression of miRNAs caused by the knockdown of circCpsf6 was revealed in the volcano plot.Heatmaps indicated the upregulated and downregulated clusters of differential miRNAs in N2A cells when circCpsf6 was silenced.

2021-08-01 | GSE164029 | GEO

mRNA sequencing of circCpsf6 silencing models in N2A cells

Project description:mRNA sequencing was performed to explore involved mRNAs when circCpsf6 was silenced in N2A cells.The differential expression of mRNAs caused by the knockdown of circCpsf6 was revealed in the volcano plot.Heatmaps indicated the upregulated and downregulated clusters of differential mRNAs when circCpsf6 was silenced in N2A cells

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miRNA sequencing of circCpsf6 silencing models in N2A cells

Project description:miRNA sequencing of circCpsf6 silencing models in N2A cells

| PRJNA688650 | ENA

miRNA sequencing of exosomes derived from N2A and APP-N2A cells

Project description:APP misexpression plays a crucial role in triggering a complex pathological cascade, leading to Alzheimer’s disease (AD). The aim of this study is for determine the influence of APP ectopic expression on the miRNA profiles of neuronal exosomes. In study, miRNA sequencing was done using the exosomes derived from N2A (control) and APP-N2A (N2A with APP overexpression).

2022-03-30 | E-MTAB-11106 | biostudies-arrayexpress

miRNA sequencing of exosomes derived from N2A and APP-N2A cells

Project description:miRNA sequencing of exosomes derived from N2A and APP-N2A cells

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circCpsf6 silencing models in N2A cells

Project description:This SuperSeries is composed of the SubSeries listed below.

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Exon array analysis of N2A cells after knocking down FUS

Project description:To analyze the role of Fus, Ewsr1, and Taf15 in alternative RNA processing, we performed exon array analysis in N2A cells using exon arrays. N2A cells were transfected with siRNA using Lipofectamine RNAiMAX (Life Technologies) according to the manufacturer’s instructions.

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Transcriptome anaylisis of WT and GFAT-1 G451E engineered N2a cells by RNA-Seq

Project description:Transcriptome of N2a cells carrying a GFAT-1 gain-of-function point mutation that results in a G451E amino acid substitution were compared to WT N2a transcriptome profiles. Three replicates of both cell lines were analyzed. Additionally WT N2a cells were treated with 10 mM GlcNAc for 24h prior to transcriptome analysis resulting in a third dataset with 3 replicates.

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