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Gene expression data of the subcutaneous adipose tissue from entire male, immunocastrated and surgically castrated pigs

ABSTRACT: Gene expression data of the subcutaneous adipose tissue from entire male, immunocastrated and surgically castrated pigs

PROVIDER: PRJNA690524 | ENA |

REPOSITORIES: ENA

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Gene expression data of the subcutaneous adipose tissue from entire male, immunocastrated and surgically castrated pigs

Project description:Differences in adipose tissue deposition and properties between pig male sex categories, i.e., entire male, immunocastrated and surgically castrated pigs are relatively well characterized, whereas the underlying genetic mechanisms are still not fully understood. To gain the knowledge about the genetic regulation of the differences in adipose tissue deposition, RNA-sequencing approach was used. A total of 83 differentially expressed genes were identified between entire male and immunocastrated pigs, 15 between immunocastrated and surgically castrated pigs and 48 between entire male and surgically castrated pigs by RNA-sequencing of the subcutaneous adipose tissue. Comparing entire male with immunocastrated or surgically castrated pigs, upregulated genes related to extracellular matrix dynamics, and downregulated genes involved in the control of lipid and carbohydrate metabolism were determinated. Moreover, differential gene expression in general indicated a high similarity between immunocastrated and surgically castrated pigs in contrast to entire males, except for several heat shock protein genes which were upregulated in entire male and immunocastrated pigs compared with surgically castrated pigs.

2021-03-03 | GSE164391 | GEO