Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Next generation sequencing analysis of control and KSR1 knockdown CRC cell line translatomes.

ABSTRACT: Next generation sequencing analysis of control and KSR1 knockdown CRC cell line translatomes.

PROVIDER: PRJNA690941 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Next generation sequencing analysis of control and KSR1 knockdown CRC cell line translatomes.

Project description:KSR1 signaling alters the translational landscape of human CRC cells to support their survival. To determine the effect of KSR1 on translatomes in colon cancer cells, we performed genome-wide polysome profiling. We stably expressed short hairpin RNA (shRNA) constructs targeting KSR1 or a non-targeting control in two K-Ras mutant CRC cell lines, HCT116 and HCT15. We isolated and quantified both total mRNA and efficiently translated mRNAs (associated with ≥ 3 ribosomes) using RNA sequencing. We used Anota2seq to calculate translation efficiency (TE) by comparing the differences in efficiently translated mRNAs to the total transcript of each mRNA.

2021-01-10 | GSE164492 | GEO

Next generation sequencing to identify PNISR regulating alternative splicing in CRC

Project description:We performed next generation sequencing between control CRC cells and CRC cells with PNISR knockdown to identify PNISR regulating alternative splicing

2022-08-19 | GSE204973 | GEO

Next generation sequencing to identify GPT1 regulating signaling pathway in CRC

Project description:We performed next generation sequencing between control CRC cells and CRC cells with GPT1 overexpression to identify GPT1 regulating signaling pathway

2024-02-07 | GSE250091 | GEO

Next Generation Sequencing of normal human intestinal epithelial cell lines, CRC cell lines and CRC cell lines with hypoxia treatment

Project description:We performed Next Generation Sequencing of normal human intestinal epithelial cell lines, CRC cell lines and CRC cell lines with hypoxia treatment to identify the differentially expressed non-coding RNAs.

2023-12-25 | GSE163868 | GEO

Next Generation Sequencing of CRC tissue

Project description:Colorectal cancer (CRC) is the third leading cause of cancer mortality worldwide. However, the underlying mechnism of cancer development remain largely unknown. The aim of this study is to analyze transcriptome expression profile to understand the molecular mechanism in CRC development.

2022-09-30 | GSE138202 | GEO

Next generation sequencing following CUX1 knockdown in erythroblasts

Project description:Next generation sequencing following CUX1 knockdown in erythroblasts

| PRJNA752767 | ENA

RNA-sequence results of knockdown ETV5 in Human CRC cell line HT29

Project description:RNA-sequence results of knockdown ETV5 in Human CRC cell line HT29

| PRJNA448571 | ENA

Next Generation Sequencing Analysis of control and knockdown of hnRNPU in RKO cells

Project description:We knockdown the control and the hnRNPU gene in the RKO cells, then extracted the total RNAs and performed the next generation sequencing. By comparing sequencing data from control and knockdown of hnRNPU cells,we profield the downstream targets of the hnRNPU gene.

2022-12-10 | GSE141771 | GEO

RNA-sequence results of knockdown ETV5 in Human CRC cell line HT29

Project description:We report the results of knockdowm ETV5 in human CRC celllines HT29, we built 3 controls and 3 experimental cases

2021-04-03 | GSE112628 | GEO

Translatomes of monocytes and macrophages

Project description:RNA modifications are essential for the establishment of cellular identity. Although increasing evidence indicates that RNA modifications control the innate immune response, their role in monocyte-to-macrophage differentiation and polarisation is unclear. We profile translatomes of monocytes and macrophages at resting, pro- and anti-inflammatory states.

2024-02-07 | GSE213204 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data