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Gene expression profiling of newly diagnosed multiple myeloma patients included in the HOVON95 clinical trial

ABSTRACT: Gene expression profiling of newly diagnosed multiple myeloma patients included in the HOVON95 clinical trial

PROVIDER: PRJNA691609 | ENA |

REPOSITORIES: ENA

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Gene expression profiling of newly diagnosed multiple myeloma patients included in the HOVON95 clinical trial

Project description:This gene expression set contains data from patients included in the HOVON95 clinical trial. Using this data the relation between a signature identifying patients with aggressive biology and clinical parameters was studied in newly diagnosed multiple myeloma patients. This dataset was used to identify the relationship between a signature for aggressive disease and clinical parameters.

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Gene expression profiling of newly diagnosed multiple myeloma patients included in the HOVON131 clinical trial

Project description:Gene expression profiling of newly diagnosed multiple myeloma patients included in the HOVON131 clinical trial

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Project description:In order to identify relevant, molecularly defined subgroups in Multiple Myeloma (MM), gene expression profiling (GEP) was performed on purified CD138+ plasma cells of 320 newly diagnosed myeloma patients included in the Dutch-Belgian/German HOVON-65/ GMMG-HD4 trial using Affymetrix Gene Chip U133 plus 2.0 arrays. Hierarchical clustering identified 10 distinct subgroups. Bone marrow plasma cell samples were obtained from 320 newly diagnosed multiple myeloma patients included in a large multicenter, prospective, randomized phase III trial (HOVON65/GMMG-HD4). Purified myeloma plasma cells samples with a monoclonal plasma cell purity > 80% were used for analysis.

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Gene expression profiling by RNA-seq of newly diagnosed multiple myeloma patients included in the HOVON143 clinical trial

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Gene expression profiling by RNA-seq of newly diagnosed multiple myeloma patients included in the HOVON95 clinical trial

Project description:Gene expression profiling by RNA-seq of newly diagnosed multiple myeloma patients included in the HOVON95 clinical trial

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A Gene Expression-Based Risk Stratification Model for Newly Diagnosed Multiple Myeloma

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2011-08-19 | E-GEOD-8991 | biostudies-arrayexpress

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