Project description:Community structure of photosynthetic picoeukaryotes differs in lakes with different trophic statuses along the middle-lower reaches of the Yangtze River Raw sequence reads

| PRJNA719723 | ENA

Arctic Picoeukaryotes

Project description:Biogeography of Arctic picoeukaryotes during summer of 2012

| PRJEB11449 | ENA

SINGLE PICOEUKARYOTES WHOLE GENOME SEQUENCE

Project description:SINGLE PICOEUKARYOTES WHOLE GENOME SEQUENCE

| PRJEB9331 | ENA

Project description:Prokaryotic associations with photosynthetic picoeukaryotes

| PRJNA608490 | ENA

A spatial transcriptomics based Label-free Method for Assessment of Human Stem Cell Distribution and Effects in a Mouse Model of Lung Fibrosis

Project description:Recently, cell therapy has emerged as a promising treatment option for various disorders. Given the intricate mechanisms of action (MOA) and heterogenous distribution in target tissues inherent to cell therapy, it is necessary to develop more sophisticated, unbiased approaches to evaluate the distribution of administered cells and the molecular changes at a microscopic level. This study introduces a label-free approach for assessing the tissue distribution of administered human mesenchymal stem cells (hMSCs) and their MOA, leveraging spatially resolved transcriptomics (ST) analysis. The hMSCs were introduced into a mouse model with lung fibrosis, followed by the manipulation of ST to visualize the spatial distribution of hMSCs within the tissue. This was achieved by capitalizing on interspecies transcript differences between human and mouse. Furthermore, the method allowed for the examination of molecular changes associated with the spatial distribution of hMSCs. Therefore, our method has the potential to serve as an effective tool for various cell-based therapeutic agents.

2024-05-01 | GSE253378 | GEO

Diversity of photosynthetic picoeukaryotes in eutrophic shallow lakes as assessed by combining flow cytometry cell-sorting and high throughput sequencing

Project description:Diversity of photosynthetic picoeukaryotes in eutrophic shallow lakes as assessed by combining flow cytometry cell-sorting and high throughput sequencing

| PRJEB31039 | ENA