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RNA sequencing of particulate metter treated melanocytes

ABSTRACT: RNA sequencing of particulate metter treated melanocytes

PROVIDER: PRJNA694119 | ENA |

REPOSITORIES: ENA

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RNA sequencing of particulate metter treated melanocytes

Project description:Purpose: Determine the mechanism of particulate matter-induced signaling in melanocytes. Method: Primary human epidermal melanocytes were treated with particulate matter (5 μg/cm2) and incubated for 24 h. Total RNA (1 ug) from melanocytes were extracted and subjected to library synthesis. Results: Particulate matter-treated melanocytes exhibited upregulation of ER stress, unfolded protein response, and melanogenesis-related molecules. Conclusion: Particulate matter-induced melanocyte signaling was well evaluated using RNA sequencing.

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