Genomics

Dataset Information

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Quantitative Analysis of Wild Type and Prmt1 adipocyte-specific KO Epididymal primary adipocyte Transcriptomes


ABSTRACT: Quantitative Analysis of Wild Type and Prmt1 adipocyte-specific KO Epididymal primary adipocyte Transcriptomes

PROVIDER: PRJNA704660 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR13778760_1.fastq.gz Fastqsanger.gz
SRR13778760_2.fastq.gz Fastqsanger.gz
SRR13778761_1.fastq.gz Fastqsanger.gz
SRR13778761_2.fastq.gz Fastqsanger.gz
SRR13778762_1.fastq.gz Fastqsanger.gz
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Publications

Depletion of <i>Prmt1</i> in Adipocytes Impairs Glucose Homeostasis in Diet-Induced Obesity.

Choi Seri S   Choi Dahee D   Lee Yun-Kyung YK   Ahn Seung Hyun SH   Seong Je Kyung JK   Chi Sung Wook SW   Oh Tae Jung TJ   Choi Sung Hee SH   Koo Seung-Hoi SH  

Diabetes 20210526 8


Protein arginine methyltransferase (PRMT) 1 is involved in the regulation of various metabolic pathways such as glucose metabolism in liver and atrophy in the skeletal muscle. However, the role of PRMT1 in the fat tissues under the disease state has not been elucidated to date. In this study, we delineate the function of this protein in adipocytes in vivo. PRMT1 expression was abundant in the white adipose tissues (WAT), which was induced upon a high-fat diet in mice and by obesity in humans. We  ...[more]

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