Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

MIA-PaCa2 cells transfected with silencer RNA against HuR and YAP1

ABSTRACT: MIA-PaCa2 cells transfected with silencer RNA against HuR and YAP1

PROVIDER: PRJNA704858 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

MIA-PaCa2 cells transfected with silencer RNA against HuR and YAP1

Project description:Purpose: To determine biological impact between silencing HuR and YAP1, in MIA-PaCa2. Methods: Expression profiling of MIA-PaCa2 cells knocked-down for HuR and YAP1 and control cells transfected with scramble siRNA.

2022-06-07 | GSE167525 | GEO

CRISPR deletion of ELAVL1 (HuR) in MIA PaCa-2 in vitro cells and in vivo tumors

Project description:To investigate the impact of the mRNA stabilty factor HuR on the pancreatic cancer transcriptome in MIA PaCa-2 in vitro cell line and in vivo tumors at multiple time points of tumor growth

2023-01-01 | GSE221250 | GEO

human hTERT-RPE1 cell spheroid : Control siRNA transfected vs. YAP1 siRNA transfected

Project description:Transcriptional profiling of human hTERT-RPE1 cell spheroids comparing Control siRNA transfected hTERT-RPE1 cell spheroids with those transfected with YAP1 siRNA.

2015-02-01 | GSE54146 | GEO

human hTERT-RPE1 cell spheroid : Control siRNA transfected vs. YAP1 siRNA transfected

Project description:Transcriptional profiling of human hTERT-RPE1 cell spheroids comparing Control siRNA transfected hTERT-RPE1 cell spheroids with those transfected with YAP1 siRNA. Two-condition experiment, Control siRNA vs.YAP1 siRNA hTERT-RPE1 cell spheroids. Biological replicates: 1 Control siRNA, 1YAP1 siRNA transfected, independently grown and harvested. Bothreplicates per array.

2015-02-01 | E-GEOD-54146 | biostudies-arrayexpress

Expression data for human colon cancer cell line HCT116 transfected with siRNA targeting YAP1.

Project description:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which is critical for regulating organ size, cell proliferation and tumor growth in mammals. YAP1 is known to be involved in tumorigenesis in several tissues, yet its role in colorectal cancer(CRC) is not established. To investigate the effect of YAP1 in CRC, we used microarrays to compared human colon cancer cell line HCT116 transfected with a control non-targeting siRNA to cells and transfected with siRNA targeting YAP1.

2018-01-01 | GSE92335 | GEO

RNA-seq of CAL-62 cells transfected with LINC00886 smart silencer and negative control

Project description:We extracted total RNA samples for high-through RNA sequencing from CAL-62 cells transfected with LINC00886 smart silencer and negative control. Then RNA-seq analyses were generated by deep sequencing using Illumina Hiseq.

2022-10-09 | GSE214782 | GEO

Comparison of gene expression between MIA PaCa-2 cells transfected with miR-4653-3p mimic and negative control cells

Project description:To identify the target of miR-4653-3p, mRNA microarray analysis was performed to compare mRNA expression between MIA PaCa-2 cells transfected with miR-4653-3p mimic and negative control cells.

2023-05-28 | E-MTAB-11813 | biostudies-arrayexpress

Gene Expression data from HuR-RIP-microarray from human PDAC, Mia PaCa-2 cell line

Project description:RNA binding protein, Human Antigen R (HuR/ELAVL1), regulates mRNA stability of key species involved in pancreatic ductal adenocarcinoma (PDAC) cell survival under conditions of chemotherapeutic stress, hypoxia, low glucose environment. We used RNA immunoprecipitation-microarray or RNP-IP from cytoplasmic extracts of PDAC cell lines exposed to chemotherpaeutic stress (olaparib and gemcitabine) to evaluate whole transcriptome gene expression profile associated with HuR and find novel trargtes associated with DNA repair functions of HuR.

2022-04-20 | GSE166951 | GEO

MIA gene family-related signaling in oral squamous cell carcinoma cells

Project description:Melanoma inhibitory activity (MIA) gene family is novel tumor-associated molecules. Although MIA gene family has several tumor progressive and/or suppressive functions, the detailed relevant signaling partners are unclear and investigated. In this study, we investigated the detailed MIA gene family-associated signaling using human oral squamous cell carcinoma cells. Human oral squamous cell carcinoma-derived HSC3 cells were transfected withãcontrol, MIA, MIA2, TANGO, MATE2, or LEMD1 siRNA. The effect on geneãknockdown was evaluated by cDNA microarray.

2016-07-01 | E-GEOD-80347 | biostudies-arrayexpress

Gene Expression data from HuR-RIP-microarray from human PDAC, Mia PaCa-2 cell line

Project description:Gene Expression data from HuR-RIP-microarray from human PDAC, Mia PaCa-2 cell line

| PRJNA702450 | ENA