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Evaluation of tofacitinib in cutaneous sarcoidosis [Olink Explore 1536]

ABSTRACT: Evaluation of tofacitinib in cutaneous sarcoidosis [Olink Explore 1536]

PROVIDER: PRJNA715584 | ENA |

REPOSITORIES: ENA

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Evaluation of tofacitinib in cutaneous sarcoidosis

Project description:Evaluation of tofacitinib in cutaneous sarcoidosis

| PRJNA715446 | ENA

Evaluation of tofacitinib in cutaneous sarcoidosis [Olink Explore 1536]

Project description:Sarcoidosis is a multisystem inflammatory disease and no molecularly targeted therapies exist. Here we evaluate the efficacy of tofacitinib (a JAK1/3 inhibitor) in an open-label trial of 10 patients with sarcoidosis and correlate clinical improvement with molecular parameters in blood and skin.

2022-03-30 | GSE169148 | GEO

Evaluation of tofacitinib in cutaneous sarcoidosis [scRNA-seq]

Project description:Evaluation of tofacitinib in cutaneous sarcoidosis [scRNA-seq]

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Evaluation of tofacitinib in cutaneous sarcoidosis [bulk RNA-seq]

Project description:Evaluation of tofacitinib in cutaneous sarcoidosis [bulk RNA-seq]

| PRJNA715582 | ENA

Evaluation of tofacitinib in cutaneous sarcoidosis [scRNA-seq]

2022-03-30 | GSE169147 | GEO

Evaluation of tofacitinib in cutaneous sarcoidosis [bulk RNA-seq]

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Molecular profiling and gene expression analysis in cutaneous sarcoidosis (CS)

Project description:Cutaneous sarcoidosis skin provides relatively non invasive access to granulomatous sarcoidosis tissue.

2011-10-13 | GSE32887 | GEO

Molecular profiling and gene expression analysis in cutaneous sarcoidosis (CS)

Project description:Cutaneous sarcoidosis skin provides relatively non invasive access to granulomatous sarcoidosis tissue. Twenty participants were enrolled: 15 with active CS and 5 healthy volunteers. Microarray analyses comparing non-LS and healthy volunteer skin with LS showed several thousand genes differentially expressed

2011-10-12 | E-GEOD-32887 | biostudies-arrayexpress

Evaluation of tofacitinib in cutaneous sarcoidosis

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-03-30 | GSE169149 | GEO

Gene expression data in CD4+ and CD8+ cells in sarcoidosis patients following antimycobacterial therapy

Project description:Many chronic cutaneous diseases associated with microbial antigens demonstrate clinical progression due to T cell hyporesponsiveness. Appropriate antimicrobial therapy restores T cell function, leading to clinical resolution. Due to the association of sarcoidosis with mycobacterial antigens, we compared the efficacy of antimycobacterial therapy with placebo in chronic cutaneous sarcoidosis.

2013-07-23 | GSE39606 | GEO

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