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DNA methylation alternations in the offspring brown adipose tissue from high fat diet dams

ABSTRACT: DNA methylation alternations in the offspring brown adipose tissue from high fat diet dams

PROVIDER: PRJNA724712 | ENA |

REPOSITORIES: ENA

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DNA methylation alternations in the offspring brown adipose tissue from high fat diet dams

Project description:Maternal high fat diet may disturb susceptibility in offspring. Brown adipose tissue from maternal high fat diet has CpG sites that exhibit differential DNA methylationregulated compared to control.

2021-07-26 | GSE173218 | GEO

DNA methylation alternations in the offspring liver from high fat diet dams

Project description:DNA methylation alternations in the offspring liver from high fat diet dams

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DNA methylation alternations in the offspring adipose from chromium restriction diet dams

Project description:Maternal chromium restriction may disturb susceptibility in offspring. Adipose from maternal chromium diet has 1214 CpG sites that exhibit differential DNA methylationregulated compared to control. We performed DNA methylation array analyses of offspring adipose from chromium restriction dams and control diet dams at 32 week (n=3 per group).

2016-09-08 | E-GEOD-82030 | biostudies-arrayexpress

Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring

Project description:We tested if minor changes in maternal non-shivering thermogenesis during pregnancy can severely alter the phenotype of the offspring already in the next generation. Therefore, male offspring of dams lacking the uncoupling protein 1 (UCP1-KO) in the thermogenic brown adipose tissue were analysed. Genome-wide expression profiling identified several alterations in the hepatic transcriptomic landscape, demonstrating that even minor differences in the demand for maternal thermogenesis profoundly and permanently alter hepatic gene activity in the adult offspring. Liver gene expression data of offspring from WT and UCP1-KO dams.

2020-11-09 | GSE145143 | GEO

Microarray expression of white adipose tissue, brown adipose tissue and liver in adult rat offspring of dams fed high-sucrose diet vs. standard diet

Project description:We established a new minimal congenic rat strain containing only a single gene, Zbtb16, from a metabolic syndrome model, the polydactylous rat (PD/Cub) strain, within the spontaneously hypertensive rat (SHR) strain genomic background. 16-week-old SHR and SHR-Zbtb16 rat dams were fed either standard diet during pregnancy and 4 weeks of lactation (control groups) or a high-sucrose diet (HSD, 70% calories as sucrose) during the same period. We have compared the transcriptome profile (GeneChip Rat Gene 2.1 ST Array Strip) in liver, brown and white adipose tissue in adult male offspring of SHR and SHR-Zbtb16 rat dams.

2019-06-28 | E-MTAB-6838 | biostudies-arrayexpress

DNA methylation alternations in the offspring liver from high fat diet dams

Project description:Maternal high fat diet may disturb susceptibility in offspring. liver from maternal high fat diet has CpG sites that exhibit differential DNA methylationregulated compared to control.

2019-11-28 | GSE136814 | GEO

DNA methylation alternations in the offspring liver from inulin early intervention dams

Project description:DNA methylation alternations in the offspring liver from inulin early intervention dams

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Gene expression alternations in the offspring rat intestine from sitagliptin-treated dams

Project description:Gene expression alternations in the offspring rat intestine from sitagliptin-treated dams

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MiRNA expression alternations in the offspring liver from chromium restriction diet dams

Project description:Maternal chromium restriction may disturb susceptibility in offspring. Liver from maternal chromium diet has 8 up- and 6 down- regulated miRNAs, compared to control.

2019-05-30 | GSE82026 | GEO

MiRNA expression alternations in the offspring adipose from chromium restriction diet dams

Project description:Maternal chromium restriction may disturb susceptibility in offspring. Adipose from maternal chromium diet has 6 up- and 8 down- regulated miRNAs, compared to control.

2019-05-30 | GSE82025 | GEO

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