Genomics

Dataset Information

0

Downregulation of CRX, a Group 3 specific oncogenic transcription factor, inhibits TGF-b/activin signaling in medulloblastoma cells


ABSTRACT: Downregulation of CRX, a Group 3 specific oncogenic transcription factor, inhibits TGF-b/activin signaling in medulloblastoma cells

PROVIDER: PRJNA730800 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR14575616.fastq.gz Fastqsanger.gz
SRR14575617.fastq.gz Fastqsanger.gz
SRR14575618.fastq.gz Fastqsanger.gz
SRR14575619.fastq.gz Fastqsanger.gz
SRR14575620.fastq.gz Fastqsanger.gz
Items per page:
1 - 5 of 11
altmetric image

Publications

Downregulation of CRX, a Group 3-specific oncogenic transcription factor, inhibits TGF-β/activin signaling in medulloblastoma cells.

Masurkar Shalaka Arun SA   Deogharkar Akash A   Bharambe Harish Shrikrishna HS   Shirsat Neelam Vishwanath NV  

Biochemical and biophysical research communications 20210627


Medulloblastoma, the most common malignant brain tumor in children, consists of four molecular subgroups WNT, SHH, Group 3, and Group 4. Group 3 has the worst survival rate among the four subgroups and is characterized by the expression of retina-specific genes. CRX, the master regulator of the photoreceptor differentiation, is aberrantly expressed in Group 3 medulloblastomas. CRX expression increased the proliferation, anchorage-independent growth, invasion potential, and tumorigenicity of medu  ...[more]

Similar Datasets

2021-08-26 | GSE174620 | GEO
| S-SCDT-EMM-2018-09830 | BioStudies
| S-EPMC6368680 | BioStudies
| S-EPMC2775954 | BioStudies
2019-01-01 | S-EPMC6685082 | BioStudies
| S-EPMC5599185 | BioStudies
| E-GEOD-24625 | BioStudies
| S-EPMC3349910 | BioStudies
| S-EPMC3916252 | BioStudies
| S-EPMC3422619 | BioStudies