Project description:We have cloned two sets of t(6;11) fusion genes with breakpoints in the majorand minor BCR of the MLL/KMT2A gene. Both setsof fusion genes were stably transfected alone or in combiantion to analyze their molecular power
Project description:We have cloned two sets of t(6;11) fusion genes with breakpoints in the majorand minor BCR of the MLL/KMT2A gene. Both setsof fusion genes were stably transfected alone or in combiantion to analyze their molecular power
Project description:We have used a constitutive MLL-AF4 fusion gene together with a inducible AF4-MLL fusion gene to investigate the power of theses fusion proteins. All transgenes were stably or transiently transfected.
Project description:We have used a constitutive MLL-AF4 fusion gene together with a inducible AF4-MLL fusion gene to investigate the power of theses fusion proteins. All transgenes were stably or transiently transfected.