Project description:We adapted the widely used digestion of chromatin with micrococcal nuclease (MNase) followed by deep sequencing to the parasite Trypanosoma cruzi, which presents numerous singularities. In this work, we use the hybrid CL Brener strain carrying two set of chromosomes from two substantially different parental strains. The hybrid strain CL Brener is composed of the Esmeraldo-like and non Esmeraldo-like haplotypes. Additionally, part of the genome was not assembled into any of the haplotypes. Sometimes the community working in the field uses just one haplotype as reference genome for simplicity. In this work, we emphasize the importance of using its whole genome as a reference. Moreover, we extended our analysis to a clonal strain, Sylvio-X10.

2023-10-23 | GSE176341 | GEO

Trypanosoma cruzi strain:CL Brener

Project description:Trypanosoma cruzi MNase-seq

| PRJNA665060 | ENA

Trypanosoma cruzi M6241 cl.6

Project description:Trypanosoma cruzi M6241 cl.6 Genome sequencing

| PRJNA169677 | ENA

Trypanosoma cruzi strain:CL Brener

Project description:A genome sequencing project from the Trypanosoma cruzi consortium

| PRJNA11755 | ENA

Trypanosoma cruzi JR cl. 4

Project description:Trypanosoma cruzi JR cl. 4 genome sequencing project