Project description:The overall goal of these experiments was to determine how human endothelial cells respond to pathogenic Leptospira interrogans. Leptospira interrogans causes leptospirosis, the most widespread zoonotic infection in the world. A hallmark of leptospirosis is widespread endothelial damage, which in severe cases leads to hemorrhage. In these experiments, we infected two endothelial cell lines with pathogenic Leptospira interrogans serovar Canicola strain Ca12-005, and as controls, with the non-pathogenic Leptospira biflexa serovar Patoc strain Pfra. As additional controls, uninfected cells were also included in the analyses.

2010-07-27 | GSE23173 | GEO

Analysis of the human endothelial cell response to pathogenic Leptospira interrogans vs. non-pathogenic Leptospira biflexa (Eahy1 data)

2010-07-27 | GSE23172 | GEO

Leptospira interrogans str. UI 12758

Project description:Leptospira interrogans str. UI 12758 Genome sequencing and assembly

| PRJNA74117 | ENA

Leptospira interrogans str. UI 08452

Project description:Leptospira interrogans str. UI 08452 Genome sequencing and assembly

| PRJNA74105 | ENA

Leptospira interrogans str. UI 13372

Project description:Leptospira interrogans str. UI 13372 Genome sequencing and assembly

| PRJNA74125 | ENA