Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Population genomics of variegated toad-headed lizard Phrynocephalus versicolor and its adaptation to the colorful sand of the Gobi Desert

ABSTRACT: Population genomics of variegated toad-headed lizard Phrynocephalus versicolor and its adaptation to the colorful sand of the Gobi Desert

PROVIDER: PRJNA742052 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Phrynocephalus versicolor

Project description:Phrynocephalus versicolor overview

| PRJNA849673 | ENA

Comparative metabolomics analysis reveals high-altitude adaptations in a toad-headed viviparous lizard, Phrynocephalus vlangalii

Project description:Extreme environmental conditions at high altitude, such as hypobaric hypoxia, low temperature, and strong UV radiation, pose a great challenge to the survival of animals. Although the mechanisms of adaptation to high-altitude environments have attracted much attention for native plateau species, the underlying metabolic regulation remains unclear. Here, we used a multi-platform metabolomic analysis to compare metabolic profiles of liver between high- and low-altitude populations of toad-headed lizards, Phrynocephalus vlangalii, from the Qinghai-Tibet Plateau. A total of 191 differential metabolites were identified, consisting of 108 up-regulated and 83 down-regulated metabolites in high-altitude lizards as compared with values for low-altitude lizards. Pathway analysis revealed that the significantly different metabolites were associated with carbohydrate metabolism, amino acid metabolism, purine metabolism, and glycerolipid metabolism. Most intermediary metabolites of glycolysis and the tricarboxylic acid cycle were not significantly altered between the two altitudes, but most free fatty acids as well as β-hydroxybutyric acid were significantly lower in the high-altitude population. This may suggest that high-altitude lizards rely more on carbohydrates as their main energy fuel rather than lipids. Higher levels of phospholipids occurred in the liver of high-altitude populations, suggesting that membrane lipids may undergo adaptive remodeling in response to low-temperature stress at high altitude. In summary, this study demonstrates that metabolic profiles differ substantially between high- and low-altitude lizard populations, and that these differential metabolites and metabolic pathways can provide new insights to reveal mechanisms of adaptation to extreme environments at high altitude.

2024-01-16 | MTBLS6900 | MetaboLights

Phrynocephalus versicolor isolate:EJN2017011

Project description:Phrynocephalus versicolor | Genome sequencing

| PRJNA738137 | ENA

Population Genomics of Variegated Toad-Headed Lizard Phrynocephalus versicolor and Its Adaptation to the Colorful Sand of the Gobi Desert.

Project description: Not available

| S-EPMC9260186 | biostudies-literature

Population genomics of variegated toad-headed lizard Phrynocephalus versicolor and its adaptation to the colorful sand of the Gobi Desert

Project description:Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of melanic variation. The goals of this study are to evaluate population evolutionary genetics associated with dark and light color variation in a lizard.

2022-06-15 | GSE179069 | GEO

Cane Toad Metamorphis

Project description:Comparison of pre and post metamorphis phases of cane toad Keywords: Developmental Stages

2008-11-27 | GSE6987 | GEO

Effects of substrate color on intraspecific body color variation in the toad-headed lizard, Phrynocephalus versicolor.

Project description: Not available

| S-EPMC6787858 | biostudies-literature

Phrynocephalus axillaris

Project description:Phrynocephalus axillaris overview

| PRJNA190726 | ENA

Phrynocephalus forsythii

Project description:Phrynocephalus forsythii overview