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RNA-seq of Human Endometrial B Cells During the Mid-luteal Phase

ABSTRACT: RNA-seq of Human Endometrial B Cells During the Mid-luteal Phase

PROVIDER: PRJNA749287 | ENA |

REPOSITORIES: ENA

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RNA-seq of Human Endometrial B Cells During the Mid-luteal Phase

Project description:We present the transcriptome analysis by RNA sequencing of endometrial B cells identifying potential B cell phenotypes and function in human endometrium during the mid-luteal phase. To achieve this, endometrial B cells were isolated from 15 endometrial biopsies, and cDNA library preparation was performed for RNA sequencing.

2021-07-24 | GSE180728 | GEO

The impact of chemerin on transcriptomic profile of swine luteal cells during mid-luteal phase of estrous cycle

Project description:The aim of the study was to investigate the influence of chemerin on the transcriptomic profile of porcine in vitro cultured luteal cells collected during the mid-luteal phase of estrous cycle.

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The impact of chemerin on transcriptomic profile of swine luteal cells during mid-luteal phase of estrous cycle

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eQTL Mapping of Mid-Secretory Phase Endometrial Cells

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Expression data from early luteal bovine endometrium

Project description:In both beef and dairy cattle, the majority of embryo loss occurs in the first 14 days following insemination. During this period, the embryo is completely dependent on its maternal uterine environment for development, growth and ultimately survival, therefore an optimum uterine environment is critical to embryo survival. We used microarrays to assess endometrial gene expression in high and low fertility heifers during the mid-luteal phase of the estrous cycle.

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eQTL Mapping of Mid-Secretory Phase Endometrial Cells

Project description:<p>We performed an unbiased genome-wide expression quantitative trait locus (eQTL) mapping study to identify common regulatory (expression) single nucleotide polymorphisms (eSNPs) in mid-secretory endometrium, corresponding to the luteal phase of the ovarian cycle. Biopsies were collected from 58 women with two or more early pregnancy losses and 53 of these samples passed all quality control. RNA was extracted from endometrial biopsies and DNA was extracted for sequencing from blood.</p> <p>Gene expression data can be found at NCBI GEO Series GSE77688.</p>

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Loss of endometrial plasticity in recurrent pregnancy loss (RNA-Seq)

Project description:In order to try and identify characteristics of gene expression in the endometrium of women suffering infertility or recurrenty miscarriage, we performed RNAseq on endometrial pipelle biopsies from 20 women. The endometrial transcriptome in the mid-luteal phase of the cycle (window of implantation) is highly divergent in women suffering infertility or miscarriages. 20 mid-luteal endometrial biopsies were analysed from infertile women and patients suffering recurrent pregnancy loss.

2015-09-16 | E-GEOD-65099 | biostudies-arrayexpress

Differential gene expression profiling of endometrium during the mid-luteal phase of the estrous cycle between repeat breeder and normal fertile cows

Project description:We investigated differential gene expression profiles of endometrium during the mid-luteal phase of the estrous cycle between repeat breeding (RB) and normally fertilized cows using microarray analysis. Caruncular (CAR) and intercaruncular (ICAR) endometrium of both ipsilateral and contralateral uterine horns to the corpus luteum were collected from RB (inseminated at least three times but not pregnant) and normally fertile cows on Day 15 of the estrous cycle. Global gene expression profiles of these endometrial samples were analyzed with a 15K custom-made oligo-microarray in cattle. Microarray analysis revealed that 405 and 397 genes were differentially expressed in CAR and ICAR of the ipsilateral uterine horn of RB, respectively when compared with normal cows. In contralateral uterine horn, 443 and 257 differentially expressed genes were identified in the CAR and ICAR of RB, respectively when compared with normal cows. In the analysis of whole uterine (combining the above four portions), RB cows showed up-regulation of 37 genes including PRSS2, GSTA3, PIPOX, CNGA1 and IGG1C and down-regulation of 39 genes including CHGA, KRT35, THBS4, CPXM2 and PRF1 compared with normal cows. Our results may suggest that local regulation of molecular mechanisms in each uterine portion contributes to normal uterine physiology.

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Loss of endometrial plasticity in recurrent pregnancy loss (RNA-Seq)

2015-09-16 | GSE65099 | GEO

VISFATIN (NAMPT) AFFECTS GLOBAL GENE EXPRESSION IN PORCINE ANTERIOR PITUITARY CELLS DURING THE MID-LUTEAL PHASE OF THE OESTROUS CYCLE

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2024-05-01 | E-MTAB-13922 | biostudies-arrayexpress

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