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Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C

ABSTRACT: Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C

PROVIDER: PRJNA750473 | ENA |

REPOSITORIES: ENA

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Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ChIP-Seq)

Project description:Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ChIP-Seq)

| PRJNA750478 | ENA

Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ATAC-Seq)

Project description:Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ATAC-Seq)

| PRJNA750480 | ENA

Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (RNA-Seq)

Project description:Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (RNA-Seq)

| PRJNA750483 | ENA

Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (RNA-Seq)

Project description:In this experiment, the effect of reduced CDX2 expression on the trophoblast stem cells (TSCs) transcriptome was assayed.

2022-07-01 | GSE181056 | GEO

Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ChIP-Seq)

Project description:In this experiment, the binding of CDX2 to chromatin in trophoblast stem cells was assayed using ChIP-seq.

2022-07-01 | GSE181055 | GEO

Loss of Cdx2 drives direct trophoblast differentiation into trophoblast giant cells via TFAP2C (ATAC-Seq)

Project description:In this experiment, the effect of reduced CDX2 expression on chromatin accessibility in trophoblast stem cells (TSCs) was assayed using ATAC-seq.

2022-07-01 | GSE181053 | GEO

ChIP-seq anlysis of Sox2, Tfap2c, and Cdx2 in trophoblast stem cells.

Project description:To understand the mechanism underlying the transcriptional regulation by Sox2, we analyzed genome-wide binding sites of Sox2, Tfap2c, and Cdx2 in trophoblast stem (TS) cells by chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq). ZHBTc4- and embryo-derived TS cell lines were maintained in the presence of FGF4 and mouse embryonic fibroblasts (MEFs).

2014-01-03 | E-GEOD-51511 | biostudies-arrayexpress

ChIP-seq anlysis of Sox2, Tfap2c, and Cdx2 in trophoblast stem cells.

2014-01-03 | GSE51511 | GEO

Trophoblast giant cell underrepresentation (sequencing)

Project description:We characterized the mouse trophoblast giant cell epigenome and gene expression profiles. We then compared these data to our data on underrepresentation in the polyploid trophoblast giant cells. We profiled 5 histone modifications (+ chromatin input) using ChIP-Seq, and digital expression profiles (3' RNA-Seq) for trophoblast giant cells derived from mouse. Furthermore, we profiled digital expression profiles (3' RNA-Seq) for in vivo trophoblast giant cells samples from e9.5 wildtype mouse trophoblast giant cells. We found that underrepresented domains in trophoblast giant cells are enriched for repressive marks and anti-correlate with active marks and transcription.

2014-05-29 | E-GEOD-50561 | biostudies-arrayexpress

Trophoblast giant cell underrepresentation (sequencing)

2014-05-29 | GSE50561 | GEO

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