Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

TIPE1 regulation on macrophage polarization

ABSTRACT: TIPE1 regulation on macrophage polarization

PROVIDER: PRJNA759608 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

TIPE1 regulation on macrophage polarization

Project description:Macrophages perform key and distinct functions in maintaining tissue homeostasis through finely tuning their polarization state.Here, we found that tumor necrosis factor-α-induced protein 8-like 1 (TIPE1) was highly expressed in macrophages and Tipe1 depletion impeded M2 polarization of macrophages. The goals of this study are to compare BMDMs from LyzM-Cre; Tipe1f/f or Tipe1f/f mice to have a further view of the potential difference.

2021-09-05 | GSE183208 | GEO

Modulation of macrophage polarization by HMB [macrophage]

Project description:Modulation of macrophage polarization by HMB [macrophage]

| PRJNA739181 | ENA

Microarray analysis of miR-511-3p regulation of macrophage polarization

Project description:Microarray analysis of miR-511-3p regulation of macrophage polarization

| PRJNA564813 | ENA

Microarray analysis of miR-511-3p regulation of macrophage polarization

Project description:The goal of this study is to identify potential mechanism in which miR-511-3p regulates macrophage polarization

2019-09-11 | GSE137120 | GEO

Expression data from macrophage maturation and polarization c-Myc in alternative macrophage activation experiments

Project description:In response to microenvironmental signals macrophages undergo different activation, indicated as classic/M1 and alternative/M2 polarization. C-Myc transcription factor could be an essential player in M2 polarization. Functional relevance of c-Myc in M2 macrophage biology is investigated by evaluating the effect of 100-58F4, on the transcriptional profile induced on human macrophages by IL-4. Human monocytes were obtained from normal donor buffy coats by two-step gradient centrifugation using Ficoll (Biochrom) and Percoll (Amersham). Non-adherent cells were discarded, and the purified monocytes were incubated for 7 days in RPMI 1640 (Biochom) supplemented with 10% FCS (HyClone) and 100 ng/mL M-CSF to obtain resting macrophages. Macrophage polarization was obtained by removing the culture medium and culturing cells in RPMI 1640 supplemented with 10% FCS and 100 ng/mL LPS plus 20 ng/mL IFN-gamma (M1 polarization) or 20 ng/mL IL-4 (M2 polarization) for 24 h. When needed, chemical inhibitors were added with IL-4.

2011-09-15 | E-GEOD-32164 | biostudies-arrayexpress

Frank2021 - Macrophage polarization

Project description:The model describes the mechanisms by which macrophages differentiate into a given phenotype. The model shows that both extracellular and intracellular signalling are both important for that process. More specifically, STAT1 activity favors macrophages polarization towards M1 phenotype and STAT6 activity favors macrophage polarization towards M2 phenotype. However, these polarizations are can be reversed by molecular signalling.

2022-05-23 | BIOMD0000001060 | BioModels

Modulation of macrophage polarization by HMB [macrophage]

Project description:to determine whether hydroxymethyl butyrate alters macrophage polarization bone marrow derived macrophages were treated with HMB alone or in combination with LPS for 48h

2021-12-29 | GSE178475 | GEO

Macrophage polarization in response to Piceatannol

Project description:Macrophage polarization in response to Piceatannol

| PRJNA515419 | ENA

Modulation of macrophage polarization by HMB

Project description:Modulation of macrophage polarization by HMB

| PRJNA739180 | ENA

Hepatocyte-controlled availability of activated TGFb reprograms macrophage polarization affecting liver injury and regeneration

Project description:We describe a distinct macrophage population, whose presence in the liver during homoeostasis depends on recruitment signals mediated by the chemokine receptor CCR2. The identified polarization state of this population closely resembles that induced in co-culture experiments, where hepatocytes are reducing the availability of TGFb to macrophages. Accordingly, disruption of TGFb signal transduction in macrophages phenocopies the influence of hepatocytes on macrophage polarization.

2022-12-31 | E-MTAB-11727 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data