Project description:The expression profiles of miRNAs in klotho-deficient and wild-type mice were examined by means of Genopal®-MICM DNA chips. The data suggested that there was a difference in the expression of miRNAs between klotho-deficient and wild-type mice.
Project description:To investigate the gene expression in brain tissues of Pla2g2e-deficient and wild-type mice, we performed gene expression profiling analysis using data obtained from Microarray of brain tissues collected from neuron-specific Pla2g2e-deficient and wild-type mice.
Project description:RNA-seq analysis were applied to elucidate the transcriptional differences of wild-type and Abcb11-deficient mice. Comparison of female Abcb11-/- (Abcb11F) and female C57BL/6J mouse (WTF) livers identified 3,652 RNA species that were differentially expressed (1,809 genes upregulated and 1,843 genes downregulated; Padj < 0.05). Comparison of liver gene expression in Abcb11F versus non-tumor tissue of female Abcb11-/- mice (NTF) revealed 47 differentially expressed genes. Cross-comparison of the lists of differentially expressed genes in Abcb11F versus WTF and in Abcb11F versus NTF revealed 36 genes common to the two data sets.
Project description:Regulation of epithelial barrier function is dependent upon precise control of cell survival and activation of inflammatory pathways in response to the enteric flora. These experiments tested differential colon gene expression relative to these pathways in wild type and STAT5b deficient mice. Keywords: Single time point in wild type and STAT5b deficient mice.
Project description:The purpose of this experiment was to compare the gene expression pattern between wild-type and Trib1-deficient macrophages in response to LPS. Keywords: Comparison of gene expression pattern between Wild-type and Trib1-deficient mice
Project description:To investigate the altered methylation cardiac-specific NPRA-deficient mice compares to wild type, methylation level alterations were detected by Arraystar Mouse m6A Single Nucleotide resolution microarray analysis (mazF-RIP) using the myocardium from NPRA-deficient (NPRA-/-) mice and wild-type (NPRA+/+) mice as control.
Project description:The expression profiles of miRNAs in klotho-deficient and wild-type mice were examined by means of GenopalM-BM-.-MICM DNA chips. The data suggested that there was a difference in the expression of miRNAs between klotho-deficient and wild-type mice. Small RNA samples prevared from 5-week-old klotho-deficient and wild-type mice were examined.