Project description:Hymenoscyphus linearis isolate chi01 was grown on potato dextrose broth for 3 weeks. RNA was extracted from the mycelial mat and the library was prepared with TruSeq Stranded mRNA LT Sample Prep Kit and sequenced with HiSeq 2500 (2x100 bp).
Project description:Primary objectives: The primary objective is to investigate circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
Primary endpoints: circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
