Genomics,Multiomics

Dataset Information

0

Homo sapiens


ABSTRACT: Alternative Isoform Regulation in Human Tissue Transcriptomes

OTHER RELATED OMICS DATASETS IN: E-GEOD-12946

PROVIDER: PRJNA79393 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR005321.fastq.gz Fastqsanger.gz
SRR005322.fastq.gz Fastqsanger.gz
SRR005324.fastq.gz Fastqsanger.gz
SRR005325.fastq.gz Fastqsanger.gz
SRR005326.fastq.gz Fastqsanger.gz
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Publications


Through alternative processing of pre-messenger RNAs, individual mammalian genes often produce multiple mRNA and protein isoforms that may have related, distinct or even opposing functions. Here we report an in-depth analysis of 15 diverse human tissue and cell line transcriptomes on the basis of deep sequencing of complementary DNA fragments, yielding a digital inventory of gene and mRNA isoform expression. Analyses in which sequence reads are mapped to exon-exon junctions indicated that 92-94%  ...[more]

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