Project description:We analyze the contribution of alternative splicing to the transcriptional complexity in adipose tissue and the development of diet-induced obesity. We use Next generation sequencing analysis of mice fed with a control chow diet or a high fat diet.

2016-09-06 | E-GEOD-76133 | biostudies-arrayexpress

Next generation sequencing analysis of epididymal adipose tissue (II)

Project description:We analyze the contribution of alternative splicing to the transcriptional complexity in adipose tissue and the development of diet-induced obesity. We use Next generation sequencing analysis of eWAT from control and Nova1 and Nova2-deficient mice fed with a control diet

2016-09-06 | E-GEOD-76294 | biostudies-arrayexpress

Next generation sequencing analysis of epididymal adipose tissue (III)

Project description:We analyze the contribution of alternative splicing to the transcriptional complexity in adipose tissue and the development of diet-induced obesity. We use Next generation sequencing analysis of eWAT from control and Nova1 and Nova2-deficient mice fed with a high fat diet.

2016-09-06 | E-GEOD-76317 | biostudies-arrayexpress

Atlas of Brown Adipose Tissue

Project description:Heterogeneity in brown adipocyte populations was observed. Until recently, thermogenic adipocytes have been considered a homogeneous population. However, studies have pointed to the existence of multiple subtypes, which are distinct in developmental origin, substrate usage and transcriptome. Our current incomplete understanding of cell types in brown and beige adipose tissue and the lack of specific markers constitute a critical barrier to studying their biological functions. Our goal is to use the advances in single-cell genomics to determine subtypes that constitute adipose tissue under various thermogenic stimuli at the single cell resolution.

2020-02-04 | GSE144720 | GEO

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