Project description:We tested the ability of helminth Taenia crassiceps parasite excreted/secreted products (TcES) to induce a regulatory-associated profile in bone-marrow derived macrophages (BMDMs). We also compared gene expression and microRNA profile of BMDMs exposed to TcES with those exposed to LPS which elicits a well-known inflammatory program.
Project description:We tested the ability of helminth Taenia crassiceps parasite excreted/secreted products (TcES) to induce a regulatory-associated profile in bone-marrow derived macrophages (BMDMs). We also compared gene expression and microRNA profile of BMDMs exposed to TcES with those exposed to LPS which elicits a well-known inflammatory program.
Project description:sRNA profiling from adult Taenia multiceps by Illumina high-throughput sequencing was used to increase our understanding of the molecular regulation mechanisms of the cestode,find novel biomarkers for the parasitic disease and search new strategies to control these parasites. examination of 6 individuals of adult stage of Taenia multiceps (pooled)
