Project description:To gain insight into the auxin-dependent network during flower initiation, we used complementary RNAseq-based genomic analyses to obtain a global vision of the auxin-regulated gene network in the SAM before progressively converging on the identification of a high-confidence core network acting during the early phases of flower initiation.

2022-06-08 | GSE205298 | GEO

Transcriptional Reprogramming during Floral Fate Acquisition

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-06-08 | GSE205299 | GEO

Geminin represses mesendoderm cell fate acquisition in embryoid bodies

Project description:Geminin is a small nucleoprotein that neuralizes ectoderm in the Xenopus embryo. Geminin promotes neural fate acquisition of mouse embryonic stem cells: Geminin knockdown during neural fate acquisition decreased expression of neural precursor cell markers (Pax6, Sox1), while increasing expression of Pitx2, Lefty1 and Cited2, genes involved in formation of the mouse node. Here we differentiated mouse embryonic stem cells into embryoid bodies to study Geminin's ability to repress primitive streak mesendoderm fate acquisition. We used microarrays to define the sets of genes that are regulated by Geminin during cell fate acquisition in embryoid bodies, using Dox-inducible Geminin knockdown or overexpression mouse embryonic stem cell lines. ES cell lines for Geminin over-expression (GemOE) were treated without or with Dox from day 3 to day 5 of EB differentiation and were collected on days 4 or 5 for microarray analysis. Gem knockdown (KD) ES cell lines were treated without or with Dox from day 0 to day 4 of EB differentiation and were collected on day 4 for microarray analysis.

2014-07-01 | E-GEOD-39676 | biostudies-arrayexpress

Transcriptional Reprogramming during Floral Fate Acquisition II

2022-06-08 | GSE205296 | GEO

Transcriptional Reprogramming during Floral Fate Acquisition I

2022-06-08 | GSE205295 | GEO

Geminin represses mesendoderm cell fate acquisition in embryoid bodies

2014-07-01 | GSE39676 | GEO

Tox4 Modulates Cell Fate Reprogramming

Project description:Tox4 Modulates Cell Fate Reprogramming

| PRJNA525830 | ENA