Dataset Information

Drosophila melanogaster

ABSTRACT: dmyc overexpression 7h and 14h

ORGANISM(S): Drosophila melanogaster

PROVIDER: PRJNA91275 | ENA |

REPOSITORIES: ENA

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Publications

Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.

Grewal Savraj S SS Li Ling L Orian Amir A Eisenman Robert N RN Edgar Bruce A BA

Nature cell biology 20050220 3

Regulating ribosome number is thought to control cellular growth. Synthesis of ribosomal RNA (rRNA) is a limiting step in ribosome biogenesis and rates of rRNA synthesis are generally altered depending on the growth status of a cell. Although studies in unicellular systems have addressed the mechanisms by which this occurs, few studies have applied a genetic approach to examine growth-dependent control of rRNA synthesis in metazoans. Here, we show that in Drosophila melanogaster Myc (dMyc) is a ...[more]

PMID: 15723055

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