Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
PROVIDER: PRJNA91275 | ENA |
REPOSITORIES: ENA
Grewal Savraj S SS Li Ling L Orian Amir A Eisenman Robert N RN Edgar Bruce A BA
Nature cell biology 20050220 3
Regulating ribosome number is thought to control cellular growth. Synthesis of ribosomal RNA (rRNA) is a limiting step in ribosome biogenesis and rates of rRNA synthesis are generally altered depending on the growth status of a cell. Although studies in unicellular systems have addressed the mechanisms by which this occurs, few studies have applied a genetic approach to examine growth-dependent control of rRNA synthesis in metazoans. Here, we show that in Drosophila melanogaster Myc (dMyc) is a ...[more]