Genomics

Dataset Information

0

Saccharomyces cerevisiae


ABSTRACT: yeast hsf1-R206S/F256S mutant

ORGANISM(S): Saccharomyces cerevisiae  

PROVIDER: PRJNA91799 | ENA |

REPOSITORIES: ENA

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Publications

Identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in Saccharomyces cerevisiae.

Yamamoto Ayako A   Mizukami Yu Y   Sakurai Hiroshi H  

The Journal of biological chemistry 20050111 12


In response to hyperthermia, heat shock transcription factor (HSF) activates transcription of a set of genes encoding heat shock proteins (HSPs). The promoter regions of HSP genes contain the HSF binding sequence called the heat shock element (HSE), which consists of contiguous inverted repeats of the sequence 5'-nGAAn-3' (where n is any nucleotide). We have constructed an hsf1 mutant of Saccharomyces cerevisiae and analyzed genome-wide changes in heat shock response in the mutant cells. The res  ...[more]

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