Genomics

Dataset Information

0

Rattus norvegicus


ABSTRACT: Chronic contusion spinal cord injury in rats

ORGANISM(S): Rattus norvegicus  

PROVIDER: PRJNA92013 | ENA |

REPOSITORIES: ENA

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Publications

Spatial and temporal gene expression profiling of the contused rat spinal cord.

Aimone James B JB   Leasure J Leigh JL   Perreau Victoria M VM   Thallmair Michaela M  

Experimental neurology 20041001 2


Microarray technology was used to examine gene expression changes following contusive injury of the adult rat spinal cord. To obtain a global understanding of the changes triggered by the injury, differential gene expression was examined spatially, using tissue samples from the epicenter of injury as well as 1 cm rostral and 1 cm caudal to the epicenter, and temporally, at 3 h, 24 h, 7 days, and 35 days post-injury. To filter out gene expression changes that were due to the laminectomy, samples  ...[more]

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