Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: NT2 DMSO vs. RA

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA92657 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity.

Giuliano Caryl J CJ   Kerley-Hamilton Joanna S JS   Bee Tom T   Freemantle Sarah J SJ   Manickaratnam Ranjan R   Dmitrovsky Ethan E   Spinella Michael J MJ  

Biochimica et biophysica acta 20050901 1


Testicular germ cell tumors (TGCTs) are the most common carcinomas of young men aged 15-35. The molecular events involved in TGCT genesis are poorly understood. TGCTs have near universal amplification of the short arm of chromosome 12, however positional cloning efforts have not identified causative genes on 12p involved in formation or progression of TGCTs. Human embryonal carcinoma (EC) are the stem cells of TGCTs and are pluripotent. EC cells terminally differentiate toward a neuronal lineage  ...[more]

Similar Datasets

2010-12-24 | E-GEOD-16891 | ArrayExpress
| GSE20463 | GEO
2011-02-19 | E-GEOD-20463 | ArrayExpress
| PRJNA122657 | ENA
2011-08-25 | GSE23936 | GEO
2011-08-24 | E-GEOD-23936 | ArrayExpress
2010-12-24 | GSE16878 | GEO
| GSE63741 | GEO
2010-12-24 | E-GEOD-16878 | ArrayExpress
2010-09-25 | GSE24338 | GEO