Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Saccharomyces cerevisiae

ABSTRACT: Yeast translation

OTHER RELATED OMICS DATASETS IN: BIOMD0000000626

PROVIDER: PRJNA93891 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Regulation of translation under mitoprotein-induced stress in Saccharomyces cerevisiae

Project description:Proteotoxic stress triggers adaptive cellular responses, including changes in gene expression on the levels of transcription and translation. In this study, we analyzed the translational response of yeast cells to impaired protein import into mitochondria, a condition under which mitochondrial precursor proteins accumulate in the cytosol and impose proteotoxic stress. We analyzed changes in translational efficiency as well as more subtle changes in the distribution of ribosomes along transcripts, with a special focus on translation initiation sites.

2021-12-14 | GSE172017 | GEO

Saccharomyces cerevisiae

Project description:Translation initiation factor eIF4G1 preferentially binds yeast transcript leaders containing conserved oligo-uridine motifs

| PRJNA345383 | ENA

Saccharomyces cerevisiae

Project description:Yeast aging study

| PRJNA84987 | ENA

Saccharomyces cerevisiae

Project description:Yeast glucosamine treatment

| PRJNA85025 | ENA

Saccharomyces cerevisiae

Project description:yeast wt pool

| PRJNA179386 | ENA

MNase-seq Experiments from Saccharomyces cerevisiae

Project description:MNase-seq Experiments from Calorie Restricted and Non-Restricted Yeast from WT, ISW2DEL and ISW2K215R strains

2014-09-15 | GSE53718 | GEO

Saccharomyces cerevisiae

Project description:Improved ribosome-footprint and mRNA measurements provide insights into dynamics and regulation of yeast translation

| PRJNA305643 | ENA

Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae

Project description:Aneuploidy and aging are correlated; however, a causal link between these two phenomena has remained elusive. Here we show that yeast disomic for a single native yeast chromosome generally have a decreased replicative lifespan. In addition, the extent of this lifespan deficit correlates with the size of the extra chromosome. We identified a mutation in BUL1 that rescues both the lifespan deficit and a protein trafficking defect in yeast disomic for chromosome 5. Bul1 is an E4 ubiquitin ligase adaptor involved in a protein quality-control pathway that targets membrane proteins for endocytosis and destruction in the lysosomal vacuole thereby maintaining protein homeostasis. Concurrent suppression of the aging and trafficking phenotypes suggests that disrupted membrane protein homeostasis in aneuploid yeast may contribute to their accelerated aging. The data reported here demonstrate that aneuploidy can impair protein homeostasis, shorten lifespan, and may contribute to age-associated phenotypes.

2015-12-04 | GSE75623 | GEO

Saccharomyces cerevisiae

Project description:Nucleosome positioning in Yeast

| PRJNA227459 | ENA

Saccharomyces cerevisiae

Project description:Yeast Membrane Bound Polysome

| PRJNA92727 | ENA