Genomics

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Borreliella burgdorferi


ABSTRACT: Transcriptional p of B. burgdorferi containing a unique bosR allele identifies a putative oxidative stress regulon

ORGANISM(S): Borreliella burgdorferi  

PROVIDER: PRJNA95857 | ENA |

REPOSITORIES: ENA

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Transcriptional profiling of Borrelia burgdorferi containing a unique bosR allele identifies a putative oxidative stress regulon.

Hyde Jenny A JA   Seshu J J   Skare Jonathan T JT  

Microbiology (Reading, England) 20060901 Pt 9


Borrelia burgdorferi regulates gene expression in response to environmental conditions, including temperature, pH, redox potential and host factors. B. burgdorferi encodes a PerR homologue designated BosR, which presumably serves as a global regulator of genes involved in the oxidative stress response. Infectious B. burgdorferi strain B31 is resistant to oxidative stressors in vitro, whereas the non-infectious isolate was sensitive due, in part, to a point mutation that converts an arginine to a  ...[more]

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