Mus musculus
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA98109 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Transcriptional comparison between whole kidneys from E14.5 Wnt4 mutants and wildtype mice (MG_U74Av2 platform). (GUDMAP Series ID: 7)
| PRJNA100595 | ENA
Project description:Our laboratory's interest is in understanding the molecular principles that underlie the regional organization of the mammalian metanephric kidney. Our goal is to generate a detailed spatial map of the cellular expression of selected regulatory genes during mammalian kidney development. The goal of this study is to identify a population of genes that are enriched in the renal vesicle (RV) and its derivatives using Wnt4 mutants. Experiment Overall Design: Wnt4 is required for renal vesicle (RV) induction. Therefore, RV and the derivatives (s-shaped body and eventually the mature nephron) are missing in Wnt4 mutants. At E14.5, these structures are present in wildtype kidneys. Transcriptional profile comparison between E14.5 wildtype and Wnt4 mutants therefore identify genes expressed in the RV and derivatives. Minimally pooled kidney samples were used as single biological replicates. Total RNA was isolated from these pools and subjected to a single round of amplification for use on Affymetrix arrays.
2008-06-14 | E-GEOD-6288 | biostudies-arrayexpress
Project description:Our laboratory's interest is in understanding the molecular principles that underlie the regional organization of the mammalian metanephric kidney. Our goal is to generate a detailed spatial map of the cellular expression of selected regulatory genes during mammalian kidney development. The goal of this study is to identify a population of genes that are enriched in the renal vesicle (RV) and its derivatives using Wnt4 mutants. Experiment Overall Design: Wnt4 is required for renal vesicle (RV) induction. Therefore, RV and the derivatives (s-shaped body and eventually the mature nephron) are missing in Wnt4 mutants. At E14.5, these structures are present in wildtype kidneys. Transcriptional profile comparison between E14.5 wildtype and Wnt4 mutants therefore identify genes expressed in the RV and derivatives. Minimally pooled kidney samples were used as single biological replicates. Total RNA was isolated from these pools and subjected to a single round of amplification for use on Affymetrix arrays.
2008-06-15 | E-GEOD-6934 | biostudies-arrayexpress
Project description:Transcriptional profile of E14.5 micro-dissected kidney structures: renal vesicle, s-shaped body & collecting duct (MG_U74Av2 platform). (GUDMAP Series ID: 9)
| PRJNA100515 | ENA
Project description:Transcriptional profile of E14.5 micro-dissected kidney structures: renal vesicle, s-shaped body & collecting duct (MOE430A platform). (GUDMAP Series ID: 8)
| PRJNA100593 | ENA
Project description:Wildtype C57BL/6 mice kidneys from E14.5, E18.5, P3, and adult were isolated. Proteins were sequentially fractionated and the CS and IN fractions were processed and analyzed using mass spectrometry.
2020-06-21 | MSV000085616 | MassIVE
Project description:Gene expression profiles of adult renal capsule isolated from kidneys using micro-dissection. (GUDMAP Series ID: 36)
| PRJNA124861 | ENA
Project description:Gene expression profiles of E15 ureter. (GUDMAP Series ID: 26)
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Project description:Gene expression profiles of E13 bladder compartments. (GUDMAP Series ID: 24)
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Project description:Gene expression profiles of neonatal bladder samples. (GUDMAP Series ID: 19)
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