Project description:caArray_EXP-608: TCGA (Laml): Analysis of RNA Expression Array Data for Acute Myeloid Leukemia Using Affymetrix HG-U133 Plus 2.0 (WUSTL)
Project description:The aim of the study was to get insights into transcriptional alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients We compared the global gene expression profile from AML BM-MSC (n=19) to healthy donor (HD) controls (HD BM-MSC n=4) AML BM-MSC and HD BM-MSC were isolated from bone marrow aspirates (see below) and hybridized on an Affymetrix HG-U133 Plus 2.0 GeneChip
Project description:AC133+ cell fractions were isolated from bone marrow of 33 acute myeloid leukemia patients and 10 healthy donors and their transcriptional profiles assessed with Affymetrix GeneChip Human Genome U133 Plus 2.0