Homo sapiens
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA99395 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Congenital heart disease (CHD) is the most frequent birth defect and affects nearly 1% of newborns. The etiology of CHD is largely unknown and only a small percentage can be assigned to environmental risk factors such as maternal diseases or exposure to mutagenic agents during pregnancy. Chromosomal imbalances have been identified in many forms of syndromic CHD, but next to nothing is known about the impact of DNA copy number changes in non-syndromic CHD. Here we present a sub-megabase resolution array CGH screen of a cohort with CHD as the sole abnormality at the time of diagnosis. Keywords: array CGH In this BAC array CGH study 104 patients with congenital heart disease and some of their parents were screened for DNA copy number changes at submegabase resolution. No dye swap was performed.
2008-05-11 | E-GEOD-7527 | biostudies-arrayexpress
Project description:Developmental Mechanisms of Human Congenital Heart Disease
| PRJNA380446 | ENA
Project description:PCGC: Congenital Heart Disease Genetic Network Study
| PRJNA183422 | ENA
Project description:Screening for chromosomal aberrations by array CGH in 74 patients with congenital hypothyroidism
| PRJNA119487 | ENA
Project description:An experimental loop design improves the detection of congenital chromosomal aberrations by array CGH
| PRJNA98579 | ENA
Project description:Congenital heart disease (CHD) is the most frequent birth defect and affects nearly 1% of newborns. The etiology of CHD is largely unknown and only a small percentage can be assigned to environmental risk factors such as maternal diseases or exposure to mutagenic agents during pregnancy. Chromosomal imbalances have been identified in many forms of syndromic CHD, but next to nothing is known about the impact of DNA copy number changes in non-syndromic CHD. Here we present a sub-megabase resolution array CGH screen of a cohort with CHD as the sole abnormality at the time of diagnosis. Keywords: array CGH
2008-05-12 | GSE7527 | GEO
Project description:Kids First Pediatric Research Program in Congenital Heart Disease
| PRJNA324734 | ENA