Proteomics

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Targeted quantification of phosphorylation sites in S. macrospora wildtype and STRIPAK-mutants


ABSTRACT: The composition of the striatin-interacting phosphatases and kinases (STRIPAK) signaling complex is highly similar in all eukaryotes and controls for the phosphorylation and dephosphorylation of target proteins. Associated with STRIPAK are germinal center kinases (GCK), some of which are part of conserved downstream signaling pathways. Using protein samples from wild type and three STRIPAK mutants, we applied absolute quantification by parallel reaction monitoring (PRM) to analyse phosphorylation site occupancies.

ORGANISM(S): Sordaria Macrospora

SUBMITTER: Bernhard Blank-Landeshammer  

PROVIDER: PXD023130 | panorama | Thu Apr 15 00:00:00 BST 2021

REPOSITORIES: PanoramaPublic

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