Proteomics

Dataset Information

557

M.musculus - Liver, SC (Huttlin,cell,2010)


ABSTRACT: abundance based on Spectral counting, fromHuttlin,cell, 2010
Interaction consistency score: 14.3 Coverage: 22

SUBMITTER: Christian von Mering   

PROVIDER: 10090125 | PAXDB| 12/03/2015

REPOSITORIES: PAXDB

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Publications

PaxDb, a database of protein abundance averages across all three domains of life.

Wang M M   Weiss M M   Simonovic M M   Haertinger G G   Schrimpf S P SP   Hengartner M O MO   von Mering C C  

Molecular & cellular proteomics : MCP 20120424 8


Although protein expression is regulated both temporally and spatially, most proteins have an intrinsic, "typical" range of functionally effective abundance levels. These extend from a few molecules per cell for signaling proteins, to millions of molecules for structural proteins. When addressing fundamental questions related to protein evolution, translation and folding, but also in routine laboratory work, a simple rough estimate of the average wild type abundance of each detectable protein in  ...[more]

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