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M.musculus - Suprachiasmatic nucleus, iBAQ (Chiangetal,plosgenetics.2014)

ABSTRACT: abundance based on iBAQ, Interaction consistency score: 15.5, Coverage: 18

ORGANISM(S): 10090

SUBMITTER: Christian von Mering

PROVIDER: 1300563876 | PAXDB | 2014

REPOSITORIES: PAXDB

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			Action	DRS
	bioprojects-abundance-files-v4.0.zip	Other

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Publications

The proteomic landscape of the suprachiasmatic nucleus clock reveals large-scale coordination of key biological processes.

Chiang Cheng-Kang CK Mehta Neel N Patel Abhilasha A Zhang Peng P Ning Zhibin Z Mayne Janice J Sun Warren Y L WY Cheng Hai-Ying M HY Figeys Daniel D

PLoS genetics 20141016 10

The suprachiasmatic nucleus (SCN) acts as the central clock to coordinate circadian oscillations in mammalian behavior, physiology and gene expression. Despite our knowledge of the circadian transcriptome of the SCN, how it impacts genome-wide protein expression is not well understood. Here, we interrogated the murine SCN proteome across the circadian cycle using SILAC-based quantitative mass spectrometry. Of the 2112 proteins that were accurately quantified, 20% (421 proteins) displayed a time- ...[more]

PMID: 25330117

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