Proteomics

Dataset Information

0

Mmulatta - Cardiac ventricle, normalized spectral counts (Kaushiketal,scitranslmed2015)


ABSTRACT: abundance based on normalized spectral counts, Interaction consistency score: 2.2, Coverage: 4

ORGANISM(S): 9544

SUBMITTER: Christian von Mering  

PROVIDER: 14227165 | PAXDB | 2015

REPOSITORIES: PAXDB

Dataset's files

Source:
Action DRS
bioprojects-abundance-files-v4.0.zip Other
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Publications


The human heart is capable of functioning for decades despite minimal cell turnover or regeneration, suggesting that molecular alterations help sustain heart function with age. However, identification of compensatory remodeling events in the aging heart remains elusive. We present the cardiac proteomes of young and old rhesus monkeys and rats, from which we show that certain age-associated remodeling events within the cardiomyocyte cytoskeleton are highly conserved and beneficial rather than del  ...[more]

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