Dataset Information

M.tuberculosis - Whole organism, absolute concentration (Schubertetal,cellhostmicrobe2014)

ABSTRACT: abundance based on absolute concentration, Interaction consistency score: 1.0, Coverage: 46

ORGANISM(S): 83332

SUBMITTER: Christian von Mering

PROVIDER: 2118471723 | PAXDB | 2014

REPOSITORIES: PAXDB

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Dataset's files

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			Action	DRS
	bioprojects-abundance-files-v4.0.zip	Other

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Publications

The Mtb proteome library: a resource of assays to quantify the complete proteome of Mycobacterium tuberculosis.

Schubert Olga T OT Mouritsen Jeppe J Ludwig Christina C Röst Hannes L HL Rosenberger George G Arthur Patrick K PK Claassen Manfred M Campbell David S DS Sun Zhi Z Farrah Terry T Gengenbacher Martin M Maiolica Alessio A Kaufmann Stefan H E SHE Moritz Robert L RL Aebersold Ruedi R

Cell host & microbe 20130501 5

Research advancing our understanding of Mycobacterium tuberculosis (Mtb) biology and complex host-Mtb interactions requires consistent and precise quantitative measurements of Mtb proteins. We describe the generation and validation of a compendium of assays to quantify 97% of the 4,012 annotated Mtb proteins by the targeted mass spectrometric method selected reaction monitoring (SRM). Furthermore, we estimate the absolute abundance for 55% of all Mtb proteins, revealing a dynamic range within th ...[more]

PMID: 23684311

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