Proteomics

Dataset Information

0

M.tuberculosis - Whole organism, SC (Albrethsen,mcp,2013)


ABSTRACT: abundance based on Spectral counting, Interaction consistency score: 5.5, Coverage: 29

ORGANISM(S): 83332

SUBMITTER: Christian von Mering  

PROVIDER: 4068500525 | PAXDB | 2013

REPOSITORIES: PAXDB

Dataset's files

Source:
Action DRS
bioprojects-abundance-files-v4.0.zip Other
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Publications

Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems.

Albrethsen Jakob J   Agner Jeppe J   Piersma Sander R SR   Højrup Peter P   Pham Thang V TV   Weldingh Karin K   Jimenez Connie R CR   Andersen Peter P   Rosenkrands Ida I  

Molecular & cellular proteomics : MCP 20130123 5


In order to successfully enter the latent stage, Mycobacterium tuberculosis must adapt to conditions such as nutrient limitation and hypoxia. In vitro models that mimic latent infection are valuable tools for describing the changes in metabolism that occur when the bacterium exists in a non-growing form. We used two complementary proteomic approaches, label-free LC-MS/MS analysis and two-dimensional difference gel electrophoresis, to determine the proteome profile of extracellular proteins from  ...[more]

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