Browse
Submit Data
Databases
API
Help

Dataset Information

8 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

YAGmem48

ABSTRACT: enrichment for membrane proteins; 400-800 m/z; Goo et al., 2003, Mol Cell Proteomics 2(8):508

OTHER RELATED OMICS DATASETS IN: PXD000134PRJNA136559PRJNA142175PRJNA142177

INSTRUMENT(S): Unknown

ORGANISM(S): Halobacterium Nrc-1 (halobacterium)

SUBMITTER: Y. A. Goo, E. C. Yi, N. S. Baliga, W. A. Tao, M. Pan, R. Aebersold, D. R. Goodlett, L. Hood and W. V. Ng

PROVIDER: PAe000251 | PeptideAtlas | 2011-12-31

REPOSITORIES: PeptideAtlas

ACCESS DATA

Json Xml

Publications

The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells.

Munoz Javier J Low Teck Y TY Kok Yee J YJ Chin Angela A Frese Christian K CK Ding Vanessa V Choo Andre A Heck Albert J R AJ

Molecular systems biology 20111122

Assessing relevant molecular differences between human-induced pluripotent stem cells (hiPSCs) and human embryonic stem cells (hESCs) is important, given that such differences may impact their potential therapeutic use. Controversy surrounds recent gene expression studies comparing hiPSCs and hESCs. Here, we present an in-depth quantitative mass spectrometry-based analysis of hESCs, two different hiPSCs and their precursor fibroblast cell lines. Our comparisons confirmed the high similarity of h ...[more]

PMID: 22108792

Similar Datasets

Ovarian cell lines

Project description:Schaner, M., et al. Mol Biol Cell. 2003 Nov;14(11):4376-86. Figure 1 Ovarian Cell Lines Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: Logical Set

2006-02-25 | GSE4197 | GEO

Ovarian cancers

Project description:Schaner M., et al.; Mol Biol Cell. 2003 Nov;14(11):4376-86. Figure 1 Unsupervised hierarchical clustering of ovarian cell lines and ovarian cancers. Cell lines were not co-clustered with the tumor specimens, because these cell lines have a very prominent proliferation cluster (Perou et al., 1999; Ross et al., 2000) that significantly influences the clustering of the tumor samples if the two sample sets are not analyzed separately. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: Logical Set

2006-02-25 | GSE4198 | GEO

FAIRE-chip in MCF7 and LNCaP

Project description:The compaction degree of chromatin is intimately related to its functionality and active cis-regulatory elements typically exist within open chromatin regions depleted in nucleosomes (Heintzman et al. 2007; Boyle et al. 2008). These domains can be identified using Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) that allows for enrichment of nucleosome-depleted genomic regions when cross-linked chromatin is subjected to phenol-chloroform extraction (Nagy et al. 2003; Hogan et al. 2006) Here, chromatin structure was analyzed in MCF7 and LNCaP cells using Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) (Nagy et al. 2003; Hogan et al. 2006) Keywords: FAIRE-chip

2009-01-07 | GSE11579 | GEO

Ovarian cell lines

2006-02-24 | E-GEOD-4197 | biostudies-arrayexpress

11 human cell lines - Comparative proteomic analysis of eleven common cell lines reveals ubiquitous but varying expression of most proteins

Project description:Re-submission of raw data from Geiger T et. al., Comparative proteomic analysis of eleven common cell lines reveals ubiquitous but varying expression of most proteins. Mol Cell Proteomics. 2012 Mar;11(3):M111.014050. doi: 10.1074/mcp.M111.014050. Epub 2012 Jan 25.

2015-07-21 | PXD002395 | Pride

Breast and ovarian carcinoma

Project description:Schaner, M., et al.; Mol Biol Cell. 2003 Nov;14(11):4376-86. Figure 4 Clustering of breast and ovarian carcinoma cases. 68 breast and 57 ovarian cases were co-clustered to discern both similarities and disparities between the two sample sets. An ovarianspecific set of highly expressed transcripts was identified in comparison to breast across the 3363 transcripts. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: Logical Set

2006-02-25 | GSE4268 | GEO

Involvement of transcription factor early growth response 4 (EGR4) in lung cancer bone metastasis

Project description:EGR4 (early growth response 4), a transcription factor, was previously shown to be up-regulated in lung cancer bone metastasis, compared with its expression in metastasis in other organs, using a multiorgan metastasis model of human small-cell lung cancer cells (SBC-5) in NK cell-depleted SCID mice (Kakiuchi S et al. Mol Cancer Res 2003). Here we show that EGR4 was essential for survival cancer cells, and migration ability. Next, in searching of downstream genes regulated by EGR4, we analyzed the changes in transcriptomes of SBC-5 cells at different time-points (24, 48 and 72 hr) when knockdown of EGR4 by siRNA. Lots of genes were identified either up-regulated or down-regulated in siEGR4 samples compared with control siRNA. Among these genes, there were genes with roles in metastasis or bone biology. The fact that EGR4 knockdown led to up-regulation or suppression of these genes also indicated dual roles of EGR4 in transcriptional regulation, which is consistent with previous reports: EGR4 may repress its own promoter (Zipfel PF et al. Biochim Biophys Acta. 1997) or activate certain inflammatory genes (Decker EL et al. Nucleic Acids Res. 2003; Wieland GD et al. J Cell Sci. 2005).

2013-04-01 | GSE40558 | GEO

Mass spectrometric analysis of proteolytic cleavage related to ArtA and PssA from Haloferax volcanii

Project description:The S-layer glycoprotein (SLG) of Haloferax volcanii has been shown to be processed and C-terminally linked to a lipid in an archaeosortase A (ArtA)-dependent manner. A C-terminal tripartite structure including a PGF motif is required for the processing of SLG as well as other substrates (Abdul Halim et al., 2013 Mol Microbiol; Abdul Halim et al., 2016 J Bact; Abdul Halim et al., 2017 J Bact; Abdul Halim et al., 2018 Mol Microbiol). In order to gain insights into the mechanism of processing, different cellular fractions (culture supernatant, membrane) from different strains (WT, ArtA KO mutant, ArtA active site mutants, PssA KO mutant) have been analyzed. C-terminal peptides of SLG as well as peptides spanning the PGF motiv were only identified in the mutants lacking processing activity.

2020-05-11 | PXD011050 | Pride

Chromosome-wide mapping of interactions of yeast nucleoporin Nup2 on chromosome VI.

Project description:This series is a complementary data set for the manuscript entitled "Nup-PI: The Nucleopore-Promoter Interactions of Genes in Yeast." (Mol. Cell, 2006). Experimental Background: Genomic interaction sites of nuclear proteins were mapped by the in vivo ChEC technique described in Schmid et al. (2004) Mol. Cell 16, 147-157. Genome-wide probes that are suitable for hybridization of microarrays were prepared. In brief, MboI restriction fragments that were internally cleaved by the MN moiety of the fusion proteins were amplified and labelled. The procedure is explained in detail in the manuscript. "Nup-PI: The Nucleopore-Promoter Interactions of Genes in Yeast." (Schmid et al., Mol. Cell 2006). Experiments: Genome-wide probes were prepared from control, uncleaved chromatin, as well as chromatin cleaved by H2b-MN and Nup2-MN. All samples were from raffinose grown cells induced for 1 hour by galactose in logarithmic growth phase. Keywords: Genome-wide ChEC analysis, Mapping of Nuclear Pore Proteins

2005-12-12 | GSE3756 | GEO

Ovarian cancers

2006-02-24 | E-GEOD-4198 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data