Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ
ORGANISM(S): Saccharomyces Cerevisiae
SUBMITTER: Amanda Paulovich
PROVIDER: PAe000324 | PeptideAtlas | 2006-12-31
REPOSITORIES: PeptideAtlas
Piening Brian D BD Wang Pei P Bangur Chaitanya S CS Whiteaker Jeffrey J Zhang Heidi H Feng Li-Chia LC Keane John F JF Eng Jimmy K JK Tang Hua H Prakash Amol A McIntosh Martin W MW Paulovich Amanda A
Journal of proteome research 20060701 7
Quantitative proteomic profiling using liquid chromatography-mass spectrometry is emerging as an important tool for biomarker discovery, prompting development of algorithms for high-throughput peptide feature detection in complex samples. However, neither annotated standard data sets nor quality control metrics currently exist for assessing the validity of feature detection algorithms. We propose a quality control metric, Mass Deviance, for assessing the accuracy of feature detection tools. Beca ...[more]