Proteomics

Dataset Information

0

Mtb_Triple_Digest

ABSTRACT: The digestive enzymes are trypsin, chymotrypsin and Lysc

INSTRUMENT(S): LTQ FT

ORGANISM(S): Mycobacterium Tuberculosis

SUBMITTER: Bell C, Smith GT, Sweredoski MJ, Hess S 

PROVIDER: PAe003636 | PeptideAtlas | 2012-12-31

REPOSITORIES: PeptideAtlas

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Publications

Characterization of the Mycobacterium tuberculosis proteome by liquid chromatography mass spectrometry-based proteomics techniques: a comprehensive resource for tuberculosis research.

Bell Christina C   Smith Geoffrey T GT   Sweredoski Michael J MJ   Hess Sonja S  

Journal of proteome research 20111130 1

Approximately, one-third of the world's population is infected with Mycobacterium tuberculosis, the causative agent of tuberculosis. Secreted and membrane proteins that interact with the host play important roles for the pathogenicity of the bacteria and are potential drug targets or components of vaccines. In this present study, subcellular fractionation in combination with membrane enrichment was used to comprehensively analyze the M. tuberculosis proteome. The proteome of the M. tuberculosis  ...[more]