Proteomics

Dataset Information

0

Hela_02_GluC


ABSTRACT: Cancer Cell line - Hela 02 Gluc

OTHER RELATED OMICS DATASETS IN: PRJEB2718

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Nagaraj N, Wisniewski JR, Geiger T, Cox J, Kircher M, Kelso J, P��bo S, Mann M 

PROVIDER: PAe003654 | PeptideAtlas | 2011-12-31

REPOSITORIES: PeptideAtlas

Dataset's files

Source:
Action DRS
PAe003654_7167_tandem.params Other
PAe003654_README Other
PAe003654_Search_Results_7167_201211201640.properties Other
PAe003654_Search_Results_7167_201211201640.tar.gz Other
PAe003654_mzML_201211201354.properties Other
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Publications

Deep proteome and transcriptome mapping of a human cancer cell line.

Nagaraj Nagarjuna N   Wisniewski Jacek R JR   Geiger Tamar T   Cox Juergen J   Kircher Martin M   Kelso Janet J   Pääbo Svante S   Mann Matthias M  

Molecular systems biology 20111108


While the number and identity of proteins expressed in a single human cell type is currently unknown, this fundamental question can be addressed by advanced mass spectrometry (MS)-based proteomics. Online liquid chromatography coupled to high-resolution MS and MS/MS yielded 166 420 peptides with unique amino-acid sequence from HeLa cells. These peptides identified 10 255 different human proteins encoded by 9207 human genes, providing a lower limit on the proteome in this cancer cell line. Deep t  ...[more]

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