Dataset Information

Hs_spindle_phospho_silac

ABSTRACT: Hs_spindle_phospho_silac

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Malik R, Lenobel R, Santamaria A, Ries A, Nigg EA, K�rner R

PROVIDER: PAe003755 | PeptideAtlas | 2009-12-31

REPOSITORIES: PeptideAtlas

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			Action	DRS
	PAe003755_7600_tandem.params	Other
	PAe003755_README	Other
	PAe003755_Search_Results_7600_201211210922.properties	Other
	PAe003755_Search_Results_7600_201211210922.tar.gz	Other
	PAe003755_mzML_201211210857.properties	Other

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Publications

Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages.

Malik Rainer R Lenobel René R Santamaria Anna A Ries Albert A Nigg Erich A EA Körner Roman R

Journal of proteome research 20091001 10

During mitosis, phosphorylation of spindle associated proteins is a key regulatory mechanism for spindle formation, mitotic progression, and cytokinesis. In the recent past, mass spectrometry has been applied successfully to identify spindle proteomes and phosphoproteomes, but did not address their dynamics. Here, we present a quantitative comparison of spindle phosphoproteomes prepared from different mitotic stages. In total, we report the identification and SILAC based relative quantitation of ...[more]

PMID: 19691289

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