Dataset Information
Hs_8plex_phospho_biorep1
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Others
SUBMITTER: Phanstiel DH, Brumbaugh J, Wenger CD, Tian S, Probasco MD, Bailey DJ, Swaney DL, Tervo MA, Bolin JM, Ruotti V, Stewart R, Thomson JA, Coon JJ
PROVIDER: PAe003798 | PeptideAtlas | 2011-12-31
REPOSITORIES: PeptideAtlas
Dataset's files
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Publications
Proteomic and phosphoproteomic comparison of human ES and iPS cells.
Nature methods 20110911 10
Combining high-mass-accuracy mass spectrometry, isobaric tagging and software for multiplexed, large-scale protein quantification, we report deep proteomic coverage of four human embryonic stem cell and four induced pluripotent stem cell lines in biological triplicate. This 24-sample comparison resulted in a very large set of identified proteins and phosphorylation sites in pluripotent cells. The statistical analysis afforded by our approach revealed subtle but reproducible differences in protei ...[more]