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HS_CSF_microvesicles

ABSTRACT: Proteomics of cerebrospinal fluid microvesicles

REANALYSIS of: PXD000608

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Others

SUBMITTER: Chiasserini D, van Weering JR, Piersma SR, Pham TV, Malekzadeh A, Teunissen CE, de Wit H, Jim�nez CR

PROVIDER: PAe005110 | PeptideAtlas | 2014-12-31

REPOSITORIES: PeptideAtlas

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Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.

Chiasserini Davide D van Weering Jan R T JR Piersma Sander R SR Pham Thang V TV Malekzadeh Arjan A Teunissen Charlotte E CE de Wit Heidi H Jiménez Connie R CR

Journal of proteomics 20140424

Extracellular vesicles (EVs) are present in human cerebrospinal fluid (CSF), yet little is known about their protein composition. The aim of this study is to provide a comprehensive analysis of the proteome of CSF EVs by electron microscopy and high resolution tandem mass spectrometry (MS/MS) in conjunction with bioinformatics. We report an extensive catalog of 1315 proteins identified in EVs isolated from two different CSF pools by ultracentrifugation, including 230 novel EV proteins. Out of 13 ...[more]

PMID: 24769233

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