Dataset Information
3T3_L1_RAW_bilayer1
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap XL
ORGANISM(S): Mus Musculus
SUBMITTER: Anja Freiwald, Christopher Weidner, Annabell Witzke, Sheng-Yu Huang, David Meierhofer and Sascha Sauer
PROVIDER: PAe005144 | PeptideAtlas | 2013-12-31
REPOSITORIES: PeptideAtlas
Publications
Comprehensive proteomic data sets for studying adipocyte-macrophage cell-cell communication.
Proteomics 20131201 23-24
Cellular communication is a fundamental process in biology. The interaction of adipocytes with macrophages is a key event in the development of common diseases such as type 2 diabetes. We applied an established bilayer cell co-culture system and comprehensive mass spectrometry analysis to detect proteome-wide the paracrine interaction of murine adipocytes and macrophages. Altogether, we identified 4486 proteins with at least two unique peptides of which 2392 proteins were informative for 3T3-L1 ...[more]
