REANALYSIS of: PXD000004
ORGANISM(S): Homo sapiens
SUBMITTER: MacDonald ML, et al.
Molecular & cellular proteomics : MCP 20120831 12
Synaptic architecture and its adaptive changes require numerous molecular events that are both highly ordered and complex. A majority of neuropsychiatric illnesses are complex trait disorders, in which multiple etiologic factors converge at the synapse via many signaling pathways. Investigating the protein composition of synaptic microdomains from human patient brain tissues will yield valuable insights into the interactions of risk genes in many disorders. These types of studies in postmortem t ...[more]